631 (Po) Children Born By Hbv Seropositive Mothers. The Role Of Gp/fd

Conference: 
Author(s): 
D. Ellinas, H. Sah, T. Agelopoulos, P. Raftopoulos, A. Mouhlia
Prinos Health Centre, General Hospital of Kavala, Greece
Text: 
BACKGROUND/AIM:
To investigate the management of newborn children, born by seropositive HBV mothers at the Kavala Hospital during the decade 1990-1999, initially by paediatricians of the hospital and afterwards by their own paediatricians or family doctors.
METHODS:
The Obstetrics clinic files were used, in order to record all the seropositive HBV women, who gave birth during the above mentioned period. The handling of the newborns was investigated using the Paediatric clinic records. Continuously an effort to locate and to contact those children was performed.
RESULTS:
From a total of 5715 deliveries, 108 seropositive mothers were found which gave birth to 122 children (21,3% of births). Contact was achieved with 103 of them (84,43%). Inspection of their health booklets indicates that 6 newborns (5,83%) were not administered HBIG immediately after birth. All the children were vaccinated for HBV but only 89 completed the procedure (at least 3 doses of the vaccine) Laboratory control (definition of HBV indexes) displayed one seropositive child (which did not receive HBIG) while high protective titers of antibodies (HBsAb >100 UI) were found in only 65 of them (63,11%). Children with low titres were given a booster, while those with inadequate doses completed the vaccination.
CONCLUSION:
A large percentage of neonatal HBV leads to chronic inflammation. Therefore a close look at children born by seropositive mothers is necessary, to assure the successful completion of their vaccination by the booster doses, plus to regularly control their immune status. The part of GP/FD in this process proves to be essential.
Literature: 
631 (PO) CHILDREN BORN BY HBV SEROPOSITIVE MOTHERS. THE ROLE OF GP/FD